Virus and Cancer

Biological Sciences
Faculty Advisor
Luwen Zhang
Contact Email
Potential UCARE Research Position?
Start Date
Paid or Volunteer
Hours Per Week

Epstein-Barr virus (EBV) is a human herpesvirus of increasing medical importance. EBV infection has been associated with the development of several human cancers. In immunocompromised individuals, such as organ transplant recipients or AIDS patients, EBV almost certainly causes two fatal cancers: post-transplantation lymphoproliferative disorder (PTLD) and AIDS-associated central nerve system (CNS) lymphoma. Other than cancers, EBV is associated with other autoimmune diseases such as systemic lupus erythematosus (SLE, or lupus) as well as multiple sclerosis (MS). Our main interests are the host-herpesvirus interactions, and our research will be a blend of virology, molecular and cellular biology, immunology, and pathology. The major focuses are:
1) The functions and regulations of host factors in viral cancer. 
2) Interaction between host immunity and herpesvirus. 
3) Genetic modification and personalize human induced pluripotent stem cells. 

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